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Role of Protein in Diabetes Management
08.07.2017Abstract from WJD (world Journal of diabetes)
A cost-effective nutritional approach to improve post-
prandial glycaemia is attractive considering the rising
burden of diabetes throughout the world. Whey
protein, a by-product of the cheese-making process,
can be used to manipulate gut function in order to
slow gastric emptying and stimulate incretin hormone
secretion, thereby attenuating postprandial glycaemic
excursions. The function of the gastrointestinal tract
plays a pivotal role in glucose homeostasis, particularly
during the postprandial period, and this review will
discuss the mechanisms by which whey protein slows
gastric emptying and stimulates release of gut peptides,
including the incretins. Whey protein is also a rich source
of amino acids, and these can directly stimulate beta
cells to secrete insulin, which contributes to the reduction
in postprandial glycaemia. Appetite is suppressed with
consumption of whey, due to its effects on the gut-brain
axis and the hypothalamus. These properties of whey
protein suggest its potential in the management of type
2 diabetes.
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